What is a common adverse reaction that may occur with leukotriene modifiers?

Leukotriene modifiers, such as montelukast, are commonly used in the management of allergic rhinitis, asthma, and certain other conditions. One significant adverse reaction associated with these medications is psychiatric disturbances. This can manifest as mood changes, anxiety, depression, and even suicidal thoughts or behavior in some patients.

The connection between leukotriene modifiers and psychiatric disturbances is of clinical importance, leading to warnings and careful monitoring in patients, particularly those with a history of psychiatric issues. Understanding this side effect helps healthcare providers navigate therapy options and discuss potential risks with patients.