What is a key consideration for theophylline therapy?

Theophylline therapy requires close monitoring of therapeutic levels due to its narrow therapeutic index. This means that there is a small range between the effective dose and the dose that could lead to toxicity. Theophylline levels must be monitored regularly to ensure that they remain within a therapeutic range to maximize its efficacy while minimizing the risk of adverse effects.

Therapeutic drug monitoring is valuable because factors such as age, smoking status, and concurrent medications can significantly affect theophylline metabolism. For instance, certain medications can either increase or decrease theophylline clearance, leading to altered serum levels. Regular checks help to adjust the dosage appropriately and ensure patient safety.

Therefore, understanding the importance of monitoring therapeutic levels is crucial in the context of theophylline therapy, making it an essential aspect of treatment management for conditions such as asthma and COPD.