What is a known serious adverse effect of Montelukast?

Montelukast is a leukotriene receptor antagonist commonly used in the treatment of allergic rhinitis and asthma. A known serious adverse effect associated with Montelukast is psychiatric effects, which can include changes in mood, depression, anxiety, and even suicidal thoughts or behavior. This concern has led to warnings on labeling and has prompted healthcare professionals to monitor patients closely, especially in populations who may already have underlying mental health issues.

The recognition of these psychiatric effects is crucial for healthcare providers when prescribing Montelukast, as it emphasizes the importance of evaluating the risk versus benefit for each individual patient. Understanding this risk also highlights the need for patient education regarding potential side effects so that they can report any concerning symptoms promptly.