Which medication is an example of a Long-Acting Muscarinic Antagonist (LAMA)?

Tiotropium is an example of a Long-Acting Muscarinic Antagonist (LAMA) because it specifically targets and blocks muscarinic receptors in the airways, leading to bronchodilation and reduced bronchospasm for an extended duration. LAMAs, like tiotropium, are used primarily in the management of chronic obstructive pulmonary disease (COPD) and sometimes asthma, offering relief from symptoms over a longer period compared to short-acting agents.

In contrast, Ipratropium is a short-acting muscarinic antagonist (SAMA), which provides relief for a shorter duration. Albuterol and Formoterol are both short-acting and long-acting beta-2 adrenergic agonists, respectively, and they work through a different mechanism focused on beta-2 receptors rather than muscarinic receptors. This distinct action of tiotropium as a LAMA makes it particularly effective for patients requiring prolonged bronchodilation in the management of respiratory conditions.