Which of the following is NOT a component of COPD exacerbation treatment?

C. Vaccination is the correct choice because it is not a direct treatment for the exacerbation of Chronic Obstructive Pulmonary Disease (COPD). COPD exacerbations are typically managed with bronchodilators to relieve airway constriction, corticosteroids to reduce inflammation, and, when appropriate, antibiotics to treat or prevent bacterial infections that can worsen respiratory symptoms.

Vaccination, while important for preventing respiratory infections such as influenza and pneumonia in COPD patients, does not directly address the acute management of an exacerbation once it occurs. Its role is primarily preventative rather than therapeutic in the context of an active exacerbation. Therefore, while vaccinations can be a crucial part of an overall management strategy for COPD, they are not a component of the immediate treatment of an exacerbation.