Which of the following is NOT an FDA-approved immunotherapy agent?

The correct answer is that Advair is not an FDA-approved immunotherapy agent. Advair is a combination medication that contains fluticasone, an inhaled corticosteroid, and salmeterol, a long-acting beta-agonist. It is primarily used for the management of asthma and chronic obstructive pulmonary disease (COPD) by helping to reduce inflammation and relax the airways, which makes breathing easier.

In contrast, Odactra, Ragwitek, and Oralair are all FDA-approved allergen immunotherapy products. Specifically, these medications are designed to treat allergies through sublingual immunotherapy, where patients are exposed to specific allergens in gradually increasing doses to build tolerance. This approach can reduce allergy symptoms over time and is a recognized treatment for allergic rhinitis caused by various environmental allergens.

Thus, Advair, being a therapeutic agent for respiratory conditions rather than an immunotherapy, clearly stands out as the option that does not belong in the category of FDA-approved immunotherapy agents.